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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUSK All Species: 15.45
Human Site: S684 Identified Species: 28.33
UniProt: O15146 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15146 NP_005583.1 869 97056 S684 S L S H S D L S M R A Q V S S
Chimpanzee Pan troglodytes Q5IS37 825 92786 V640 G P D A M I L V D G Q P R Q A
Rhesus Macaque Macaca mulatta XP_001106626 869 96940 S684 S L S H S D L S M R A Q V S S
Dog Lupus familis XP_538784 992 109405 A684 R S P G P P P A P G R P P P P
Cat Felis silvestris
Mouse Mus musculus Q61006 868 96674 S683 S L S H S D L S T R A R V S S
Rat Rattus norvegicus Q62838 868 96804 S683 S L S H S D L S T R A R V S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508938 874 97520 V689 S L S H G N L V P R M R I S S
Chicken Gallus gallus Q8AXY6 947 105570 E764 S L V Q G G L E A R A C L L N
Frog Xenopus laevis Q9PVZ4 1362 153727 D1099 M E L M A H G D L K S Y L R S
Zebra Danio Brachydanio rerio NP_001004503 941 106241 T755 S L S R D T L T S S S L V S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6K3 724 81818 Q547 A T H Q A P T Q D R L Q L N E
Honey Bee Apis mellifera XP_391863 648 74770 L472 S R L S H M D L I N I A L Q V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 N727 V E F A H H G N L R D F L R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.7 99.1 80.9 N.A. 93 93.4 N.A. 82.7 71.3 20.1 59 N.A. 29.9 33.5 N.A. 22.5
Protein Similarity: 100 42.9 99.5 82.5 N.A. 96.4 96.8 N.A. 90.2 80.9 35.5 70.7 N.A. 44.9 48.3 N.A. 40
P-Site Identity: 100 6.6 100 0 N.A. 86.6 86.6 N.A. 53.3 33.3 6.6 40 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 13.3 100 6.6 N.A. 93.3 93.3 N.A. 73.3 46.6 40 53.3 N.A. 40 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 16 16 0 0 8 8 0 39 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 8 31 8 8 16 0 8 0 0 0 0 % D
% Glu: 0 16 0 0 0 0 0 8 0 0 0 0 0 0 16 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 0 8 16 8 16 0 0 16 0 0 0 0 0 % G
% His: 0 0 8 39 16 16 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 54 16 0 0 0 62 8 16 0 8 8 39 8 0 % L
% Met: 8 0 0 8 8 8 0 0 16 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 8 0 0 0 8 8 % N
% Pro: 0 8 8 0 8 16 8 0 16 0 0 16 8 8 8 % P
% Gln: 0 0 0 16 0 0 0 8 0 0 8 24 0 16 0 % Q
% Arg: 8 8 0 8 0 0 0 0 0 62 8 24 8 16 0 % R
% Ser: 62 8 47 8 31 0 0 31 8 8 16 0 0 47 54 % S
% Thr: 0 8 0 0 0 8 8 8 16 0 0 0 0 0 0 % T
% Val: 8 0 8 0 0 0 0 16 0 0 0 0 39 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _